The antidepressants sertraline (Zoloft) and citalopram (Celexa) have been the best studied, are effective and safe in patients with heart disease, and also are available in generic forms.

Which antidepressant is best for cardiac patients?

The antidepressants sertraline (Zoloft) and citalopram (Celexa) have been the best studied, are effective and safe in patients with heart disease, and also are available in generic forms.

How do antidepressants affect the heart?

Although antidepressants are commonly used in clinical setting, numerous negative effects of antidepressants on the cardiovascular system have been reported to date, including bradycardia, tachycardia, hypertension, hypotension, orthostatic hypotension, electrocardiogram (ECG) changes, electrolyte abnormalities.

Do antidepressants help your heart?

The use of antidepressants in patients who have suffered heart attacks appears to reduce the risk of recurrent events and cardiac death, according to a large, multicenter study conducted by the National Heart, Lung and Blood Institute.

Can antidepressants mess with your heart?

A research team at Harvard-affiliated Massachusetts General Hospital has verified that several antidepressants may increase the risk of a potentially dangerous heart rhythm disturbance (arrhythmia).

Do antidepressants increase heart rate?

Antidepressants. Certain medicines used to treat depression can raise your heart rate. They include serotonin and norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine, duloxetine, and venlafaxine, and tricyclic antidepressants such as amitriptyline, clomipramine, desipramine, and others.

Do SSRI lower heart rate?

Although the effect of SSRIs on HRV is weaker than for TCAs, evidence shows that SSRIs are associated with a small decrease in HR, and an increase in one measure of HRV. The use of TCAs in depression leads to changes in HRV that are associated with increased risk of mortality.

Do antidepressants raise heart rate?

What antidepressant does not affect heart rate?

Fluvoxamine, fluoxetine and paroxetine are considered lower risk antidepressants with minimal effects on the cardiovascular system.

Does Paxil raise heart rate?

Paroxetine has been shown to be of similar efficacy to the tricyclic antidepressants but has lower cardiovascular toxicity in animal models and has no effects on heart rate, blood pressure or the electrocardiogram in healthy men receiving single 20-40 mg doses.

What is the algorithm for starting antidepressant therapy in depression?

Algorithm for Initiating Antidepressant Therapy in Depression Moderate to Severe depression (PHQ 15 or more) Depressed Mood For mild depression specific psychological treatments are preferable to antidepressants, PHQ <15 unless history of previous depressive episodes Assess within 2 weeks.

What are antidepressants used for?

Antidepressants are used in adults to treat depression, major depressive disorder (MDD), obsessive-compulsive

Which antidepressants are prescribed for nonpsychiatric indications?

norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), and monoamine oxidase inhibitors (MAOIs). Some antidepressants are prescribed exclusively for nonpsychiatric indications, such as insomnia, Parkinson’s disease, smoking cessation, and vasomotor symptoms of menopause, but these medications are not covered in this document.

Are antidepressants FDA approved?

The U.S. Food and Drug Administration (FDA) approves product labeling for prescription drugs. The MIG has identified that some providers may have prescribed antidepressant medications outside of FDA-approved product labeling for indication, age, dosage, or duration of therapy.