Abstract. Intranuclear inclusions typical of cytomegalovirus infections were first noticed in 1881 by German scientists who thought they represented protozoa. After viruses were grown in cell cultures, Weller, Smith and Rowe independently isolated and grew CMV from man and mice in 1956-1957.

Where did cytomegalovirus come from?

Abstract. Intranuclear inclusions typical of cytomegalovirus infections were first noticed in 1881 by German scientists who thought they represented protozoa. After viruses were grown in cell cultures, Weller, Smith and Rowe independently isolated and grew CMV from man and mice in 1956-1957.

How do you get cytomegalovirus infection?

CMV spreads from person to person through body fluids, such as blood, saliva, urine, semen and breast milk. There is no cure, but there are medications that can help treat the symptoms.

Is cytomegalovirus DNA or RNA virus?

Cytomegalovirus (CMV) is a double-stranded DNA virus and is a member of the Herpesviridae family.

What is the life expectancy of a child with CMV?

The age-adjusted years of potential life lost for all congenital CMV deaths was 56,355 years. The infant mortality rate associated with congenital CMV was 8.34 per 1 million infants annually (95% CI, 7.65–9.04).

Is CMV curable?

There’s no cure for CMV. The virus stays inactive in your body and can cause more problems later. This reactivation is most common in people who’ve had stem cell and organ transplants.

What happens if you are CMV positive?

The majority of children born who experience a CMV infection before birth are healthy and normal. However, 10 to 15% may have complications such as hearing loss, neurological abnormalities, or decreased motor skills. Infants who are infected with CMV after they are born rarely experience any long-term complications.

What is CMV pneumonia?

Cytomegalovirus (CMV) pneumonia is an infection of the lungs that can occur in people who have a suppressed immune system.

What organs are affected by CMV?

CMV can infect virtually any organ of the human body. The most common organs include the blood, brain, colon, eye, heart, kidney, liver, lung and stomach. In the case of an organ transplant patient, the symptoms of CMV can be easily confused with rejection.

What is cytomegalovirus?

Cytomegalovirus (CMV) (from the Greek cyto-, “cell”, and megalo-, “large”) is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Betaherpesvirinae. Humans and monkeys serve as natural hosts.

What is Cytomegalovirus (HHV-5)?

Cytomegalovirus (which means “Large Cell”, when translated from Greek cyto-, “cell”, and -megalo-, “large”) is a Virus which people get. It’s a Herpesvirus and is usually called HCMV (Human Cytomegalovirus) or Human Herpesvirus 5 (HHV-5).

What is cytomegalovirus (CMV) placentitis?

Congenital cytomegalovirus infection. Micrograph of a cytomegalovirus (CMV) infection of the placenta (CMV placentitis). The characteristic large nucleus of a CMV infected cell is seen off-centre at the bottom-right of the image.

What causes cytomegalovirus (CMV) colitis in immunocompromised patients?

Although it is known that CMV colitis is almost always caused by reactivation of latent CMV infection in immunocompromised patients, new infection of CMV or reinfection of different strain of CMV can cause colitis in immunocompetent hosts.