Tolvat 15 Tablet 4’s belongs to a group of medicines called vasopressin V2 receptor antagonist used to treat hyponatremia (low levels of sodium) in patients with heart failure, liver disease and hormonal imbalances such as Syndrome of Inappropriate Antidiuretic Hormone (SIADH).

What is Tolvat 15 used for?

Tolvat 15 Tablet 4’s belongs to a group of medicines called vasopressin V2 receptor antagonist used to treat hyponatremia (low levels of sodium) in patients with heart failure, liver disease and hormonal imbalances such as Syndrome of Inappropriate Antidiuretic Hormone (SIADH).

How do you get Tolvat 15?

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tolvat 15 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Does tolvaptan lower blood pressure?

Use of antihypertensive drugs remained similar in both study arms during the entire study. Conclusions Long-term treatment with tolvaptan gradually lowered BP compared with placebo, which may be attributed to a beneficial effect on disease progression, a continued natriuretic effect, or both.

Does tolvaptan increase blood pressure?

Tolvaptan did not cause a significant change in the heart rate or blood pressure during the study period and these findings are in line with earlier published reports on the lack of hemodynamic changes observed with the drug.

When should I take tolvaptan?

Tolvaptan (Samsca) comes as a tablet to take by mouth. It is usually taken once a day with or without food for no longer than 30 days.

Who needs tolvaptan?

According to the label of tolvaptan, all ADPKD patients older than 18 years are eligible for treatment. However, we believe that an age >50 years argues against initiation of this drug, for two main reasons. First, the age inclusion range in the TEMPO 3:4 trial was 18–50 years [10].

Can I stop tolvaptan?

If your doctor tells you to continue taking tolvaptan (Samsca) after you leave the hospital, you should not stop and re-start treatment on your own. You will need to return to the hospital when you restart the medication.

How fast does tolvaptan work?

The onset of effect is two to four hours after a dose is taken, and peak effects occur four to eight hours after administration. Taking tolvaptan with food does not appear to affect the drug’s bioavailability or its onset or duration of effect.

What is tolvaptan used for?

Tolvaptan is used to treat hyponatremia (low sodium in the blood) in patients with heart failure or syndrome of inappropriate antidiuretic hormone (SIADH). Tolvaptan is also used to slow kidney function decline in adults who are at risk of rapidly progressing autosomal dominant polycystic kidney disease (ADPKD).

What does tolvaptan treat?

What is the best treatment for low sodium?

Treatment

  • Intravenous fluids. Your doctor may recommend IV sodium solution to slowly raise the sodium levels in your blood.
  • Medications. You may take medications to manage the signs and symptoms of hyponatremia, such as headaches, nausea and seizures.

Does tolvaptan reduce kidney size?

Two large, randomized, clinical trials recently showed that tolvaptan reduced kidney growth by 45% and eGFR decline by 26% in early ADPKD (creatinine clearance >60 ml/min) over 3 years (Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and Its Outcomes 3:4 Trial [TEMPO 3:4])1 …

What is tolvat 15mg used for?

Ans: Tolvat 15 mg is used for the treatment and prevention from conditions like hyponatremia. Ques: What are the Side Effects of Tolvat 15Mg Tablet? Ans: Abdominal pain, dry mouth, sweating, dizziness and dry skin are common side effects.

What is a good substitute for tolvat 15 mg?

Substitutes. List of substitutes for Tolvat 15 mg Tablet. Hyponat-O 15 mg Tablet. Zydus Cadila. Shiokem 15 Tablet. Alkem Laboratories Ltd. Side effects. Major & minor side effects for Tolvat 15 mg Tablet. Abdominal pain or stomach pain.

What are the contraindications for tolvat 15?

Contraindications of Tolvat 15 mg Tablet Allergy This medicine is not recommended for use in patients with a known allergy to tolvaptan or any other inactive ingredients present along with it.

What are the side effects of tolvat?

Common side effects of Tolvat 1 Frequent urge to urinate 2 Nocturia (increased urge to urinate during the night) 3 Dryness in mouth 4 Increased thirst 5 Constipation More