What is the pKa of sulfonamide?
Sulfanilamide | C6H8N2O2S – PubChem.
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What is the pKa of sulfonamide?
between 5.9 and 12.6
The computed pKa values varied between 5.9 and 12.6 and correlate well with the available experimental pKa’s found in the literature. Cancerostatic aromatic sulfonamides 16-19 are generally weak acids with the acidity comparable or slightly lower than the lead sulfanilamide.
What is the chemical formula for sulfonamide?
Sulfanilamide | C6H8N2O2S – PubChem.
What is the chemical name of sulfanilamide?
Sulfanilamide sodium
| PubChem CID | 12226950 |
|---|---|
| Molecular Formula | C6H7N2NaO2S |
| Synonyms | SULFANILAMIDE SODIUM 10103-15-8 Sulfanilamide, monosodium salt UNII-4ZB6W6B524 4ZB6W6B524 More… |
| Molecular Weight | 194.19 |
| Parent Compound | CID 5333 (Sulfanilamide) |
What is the Iupac name of sulfonamide?
Sulfanilamide (also spelled sulphanilamide) is a sulfonamide antibacterial drug. Chemically, it is an organic compound consisting of an aniline derivatized with a sulfonamide group….Sulfanilamide.
| Clinical data | |
|---|---|
| show IUPAC name | |
| CAS Number | 63-74-1 |
| PubChem CID | 5333 |
| DrugBank | DB00259 |
What are examples of sulfonamides?
Examples of sulfonamides includes sulfadiazine, sulfamethizole (brand name: Thiosulfil Forte), sulfamethoxazole (Gantanol), sulfasalazine (Azulfidine), sulfisoxazole (Gantrisin), and various high-strength combinations of three sulfonamides. Sulfa drugs kill bacteria and fungi by interfering with cell metabolism.
Is sulfonamide a base or acid?
Any sulfonamide can be considered as derived from a sulfonic acid by replacing a hydroxyl group with an amine group. In medicine, the term “sulfonamide” is sometimes used as a synonym for sulfa drug, a derivative or variation of sulfanilamide. The first sulfonamide was discovered in Germany in 1932.
What is sulfonamide group?
Sulfonamide is a functional group (a part of a molecule) that is the basis of several groups of drugs, which are called sulphonamides, sulfa drugs or sulpha drugs. The original antibacterial sulfonamides are synthetic (nonantibiotic) antimicrobial agents that contain the sulfonamide group.
What is sulfonamide structure?
Structure of Sulfonamides Sulfonamides are composed of a sulfur atom that has two sets of double bonds to two oxygen atoms, a carbon-based side group, and a nitrogen atom bonded to the sulfur itself. In organic chemistry, an amide contains a carbonyl group bonded to a nitrogen atom.
What is sulfonamide used for?
Sulfonamides inhibit the growth of harmful bacteria in the body. They are used to treat a variety of infections, including urinary tract infections, skin infections, lung infections, and other bacterial and parasitic infections.
What is meant by sulfonamide?
sulfa drug, also called sulfonamide, any member of a group of synthetic antibiotics containing the sulfanilamide molecular structure. Sulfa drugs were the first chemical substances systematically used to treat and prevent bacterial infections in humans.
What is an example of a sulfonamide?
Is sulfonamide bactericidal or bacteriostatic?
Sulfonamides are synthetic, broad-spectrum bacteriostatic antibiotics. They were the first effective systemic antimicrobial agents. Their mode of action is based on the inhibition of DNA synthesis. Due to their toxicity and high adquired resistance their use is currently very low.
