Hemochromatosis has been separated into four distinct disorders – hereditary (classic) hemochromatosis, also known as HFE-related hemochromatosis; hemochromatosis type 2 (juvenile hemochromatosis); hemochromatosis type 3, also known as TFR2-related hemochromatosis; and hemochromatosis type 4, also known as ferroportin …

What are the 4 types of hemochromatosis?

Hemochromatosis has been separated into four distinct disorders – hereditary (classic) hemochromatosis, also known as HFE-related hemochromatosis; hemochromatosis type 2 (juvenile hemochromatosis); hemochromatosis type 3, also known as TFR2-related hemochromatosis; and hemochromatosis type 4, also known as ferroportin …

What are iron related diseases?

Hereditary hemochromatosis (he-moe-kroe-muh-TOE-sis) causes your body to absorb too much iron from the food you eat. Excess iron is stored in your organs, especially your liver, heart and pancreas. Too much iron can lead to life-threatening conditions, such as liver disease, heart problems and diabetes.

How many types of hemochromatosis are there?

There are four types of hereditary hemochromatosis, which are classified depending on the age of onset and other factors such as genetic cause and mode of inheritance. Type 1, the most common form of the disorder, and type 4 (also called ferroportin disease) begin in adulthood.

What is the difference between hemochromatosis and hereditary hemochromatosis?

Cause. The cause of hemochromatosis depends on whether a person has a hereditary form, an acquired form, or the neonatal form. Hereditary hemochromatosis is caused by genetic changes ( mutations or pathogenic variants) in any of several genes : Hemochromatosis type 1 is caused by pathogenic variants in the HFE gene.

What happens when ferritin is high?

High levels of ferritin can damage your joints, heart, liver, and pancreas. Too much iron is most often caused by an inherited disease called hemochromatosis. Many people with this disease never have any symptoms, especially women who lose iron through menstruation.

Can haemochromatosis be cured?

There’s currently no cure for haemochromatosis, but there are treatments that can reduce the amount of iron in your body. This can help relieve some of the symptoms and reduce the risk of damage to organs such as the heart, liver and pancreas.

What is the difference between iron and ferritin?

What is the difference between iron and ferritin? Iron is an important mineral present in red blood cells that carries oxygen to cells in the body. Ferritin on the other hand is a protein that stores iron and releases iron when the body needs it.

What is dangerously high ferritin levels symptoms?

High ferritin levels Symptoms of excess ferritin include: stomach pain. heart palpitations or chest pains. unexplained weakness.

What is Iron Disorders Institute?

Iron Disorders Institute is a 501 (c)3 national organization headquartered in Greenville, South Carolina. IDI received its non-profit status in 1998. Iron Disorders Institute’s vision is that no one should suffer or die prematurely because of Iron-Out-of-Balance™.

What are the different types of iron overload disorder?

There are several types of iron overload disorder, each with different causes: Hereditary hemochromatosis, which people may also refer to as primary or classic hemochromatosis, is one of the most common genetic conditions in the United States. Not everyone with the condition experiences symptoms.

What is the purpose of the iron deficiency Society website?

The mission of the website is to inform the public about iron disorders, especially hemochromatosis, iron deficiency with or without anemia, anemia of inflammatory response, dysmetabolic iron overload (DIOS) and iron avidity. The content is not meant to replace the advice of your physician.

Is there a connection between iron deficiency and brain health?

According to the Iron Disorders Institute, some autopsies have revealed that people with neurodegenerative diseases — such as Alzheimer’s disease, multiple sclerosis, and epilepsy — had problems with iron levels in the brain. Iron overload disorders, such as primary hemochromatosis, involve excess levels of iron building up in the body.