What is the NNT for metformin?
In the metformin group, the corresponding NNT is 14.
Table of Contents
What is the NNT for metformin?
In the metformin group, the corresponding NNT is 14.
At what HbA1c Should metformin be started?
If a patient is diagnosed with an A1c > 7%, we recommend starting metformin at that time provided no contraindications exist (eGFR < 30 ml/min/1.73 m2). The dose can be started at 500mg once daily (Qday) and titrated up slowly to avoid gastrointestinal (GI) side effects.
Why is metformin considered first-line treatment?
The UKPDS results, including glycemic-lowering efficacy, the weight benefits, the low risk for hypoglycemia, and the reduction in macrovascular complications, led to metformin becoming the preferred first-line therapy for treatment of type 2 diabetes.
What is the first-line of treatment for type 2 diabetes?
Metformin should be the first-line drug for managing type 2 diabetes. Insulin and sulfonylureas should be second line, and glitazones should be reserved for third line. Metformin is the only drug for type 2 diabetes that does not cause weight gain, which is an important advantage.
What is a high number needed to treat?
What is a good NNT? A perfect NNT would be 1. That means that for very patient treated one got better in the study who would not have otherwise without that particular intervention. The larger the number, the fewer people will be helped.
How do you calculate number needed to treat?
Calculation
- The number needed to treat is the inverse of the absolute risk reduction (ARR).
- The ARR is the absolute difference in the rates of events between a given activity or treatment relative to a control activity or treatment, ie control event rate (CER) minus the experimental event rate (EER), or ARR = CER – EER.
What A1C is prediabetes?
Within the 5.7% to 6.4% prediabetes range, the higher your A1C, the greater your risk is for developing type 2 diabetes….Diagnosing Prediabetes or Diabetes.
| Normal | Below 5.7% |
|---|---|
| Prediabetes | 5.7% to 6.4% |
| Diabetes | 6.5% or above |
Should metformin remain the first-line therapy for treatment of type 2 diabetes?
For a subset of patients with diabetes, other drugs should be considered. Generally, metformin should be considered first-line therapy, but there are many patients who have contraindications for metformin use.
Is 17 a high blood sugar level?
If your blood sugar levels are consistently high (usually above 20 mmol/L in adults and above 14 mmol/L in children), you may have moderate to severe symptoms of high blood sugar.
