What is the best medication for myositis?
Corticosteroids, often called steroids, are used to decrease inflammation in myositis. The most commonly prescribed type is prednisone; others include: cortisone, hydrocortisone, prednisone, prednisolone, methylprednisolone, triamcinolone, dexamethasone, and betamethasone. They are sold under many brand names.
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What is the best medication for myositis?
Corticosteroids, often called steroids, are used to decrease inflammation in myositis. The most commonly prescribed type is prednisone; others include: cortisone, hydrocortisone, prednisone, prednisolone, methylprednisolone, triamcinolone, dexamethasone, and betamethasone. They are sold under many brand names.
What is drug-induced myalgia?
A drug-induced, or toxic, myopathy is defined as the acute or subacute manifestation of myopathic symptoms such as muscle weakness, myalgia, creatine kinase elevation, or myoglobinuria that can occur in patients without muscle disease when they are exposed to certain drugs.
Which drugs cause myopathy?
Direct myotoxicity – Examples include alcohol, cocaine, glucocorticoids, lipid-lowering drugs, antimalarials (which are associated with vacuolar myopathies), colchicine (which is associated with vacuolar myopathies), and zidovudine (which causes a mitochondrial myopathy).
What is skeletal muscle toxicity?
Skeletal muscle toxicity was defined as having (1) isolated CK elevation without signs or symptoms; (2) diffuse myalgia without weakness; (3) proximal myopathy; or (4) rhabdomyolysis. About 40% of participants reported strenuous exercise the week before study entry.
Can drug-induced myopathy be reversed?
Potential agents which may induce toxic myopathy In contrast to many other muscle diseases, drug-induced myopathy is potentially reversible if the offending drug is removed.
Is drug-induced myopathy reversible?
Most drug-induced myopathies are reversible upon drug discontinuation if recognized early. They commonly include acute mild to severe myalgia and/or muscle weakness, sometimes accompanied by serum creatine kinase (CK) elevations.
Can myopathy be reversed?
While myopathy caused by statins can be mild and can be reversed when the medication is discontinued, it may present as rhabdomyolysis or severe muscle damage.
Is myopathy a neurological disorder?
The myopathies are neuromuscular disorders in which the primary symptom is muscle weakness due to dysfunction of muscle fiber. Other symptoms of myopathy can include include muscle cramps, stiffness, and spasm. Myopathies can be inherited (such as the muscular dystrophies) or acquired (such as common muscle cramps).
How long does it take to recover from steroid myopathy?
Corticosteroid-induced myopathy is reversible, with improvement in myopathy within 3 to 4 weeks of tapering corticosteroids, although recovery can take months to a year. Complications of corticosteroid-induced myopathy include the morbidity and subsequent mortality associated with chronic muscle weakness.
What are the symptoms of statin myopathy?
Symptoms of statin induced myopathy include fatigue, muscle pain, muscle tenderness, muscle weakness, nocturnal cramping, and tendon pain. The muscle symptoms tend to be proximal, generalised, and worse with exercise.