What are the causes of folic acid deficiency? Not eating enough foods containing folic acid (folate) is the most common cause. This occurs most often in elderly people who do not eat well. Alcohol-dependent people are another group often not eating properly.

What causes a lack of folic acid?

What are the causes of folic acid deficiency? Not eating enough foods containing folic acid (folate) is the most common cause. This occurs most often in elderly people who do not eat well. Alcohol-dependent people are another group often not eating properly.

Why might a person with sickle cell anemia have difficulty breathing?

People with sickle cell anemia can develop high blood pressure in their lungs. This complication usually affects adults. Shortness of breath and fatigue are common symptoms of this condition, which can be fatal.

What causes agglutinin?

Cold agglutinin disease (CAD) is a condition that makes your body’s immune system attack your red blood cells and destroy them. It’s triggered by cold temperatures, and it can cause problems that range from dizziness to heart failure. It’s also called cold antibody hemolytic anemia.

What are the three major crises of sickle cell disease?

Four major types of crises are recognised in sickle cell anaemia: aplastic, acute sequestration, hyper-haemolytic, and vaso-occlusive crises.

What complication most commonly occurs with folate deficiency?

What are the complications of folate deficiency?

  • megaloblastic anemia, which means the RBCs are larger than normal and not fully developed.
  • low levels of white blood cells and platelets.
  • serious birth irregularities in the spinal cord and brain of a developing fetus, which are called neural tube defects.

How does sickle cell anemia affect the lungs?

The sickled RBCs block the capillaries in the lungs resulting in decreased supply and exchange of oxygen. This further leads to the release of inflammatory mediators and adhesion molecules that cause the formation of minute clots in the blood vessel walls and hence, exacerbates the hypoxia [12].

What type of mutation causes sickle cell anemia?

Sickle cell disease is caused by mutations in the beta-globin (HBB) gene that lead to the production of an abnormal version of a subunit of hemoglobin — the protein responsible for carrying oxygen in red blood cells. This mutated version of the protein is known as hemoglobin S.

What are the primary and secondary causes of cold agglutinin?

Cold agglutinin disease can be primary (unknown cause) or secondary, due to an underlying condition such as an infection, another autoimmune disease , or certain cancers . Treatment depends on many factors including the severity of the condition, the signs and symptoms present in each person, and the underlying cause.

What vitamins are good for sickle cell?

Supplementing with vitamin C may help correct a deficiency. Antioxidant nutrients protect the body’s cells from oxygen-related damage. Many studies show that sickle cell anemia patients tend to have low blood levels of antioxidants, including carotenoids, vitamin A, vitamin E, and vitamin C, despite adequate intake.